Virtual Formulation Studio for B2B Pharma & Supplements
Design formulations, calculate powder flowability, simulate tablet presses, verify regulatory limits, and generate GMP compliance reports in a real-time, node-based workspace.
Amlodipine Besylate
Blending
Punch 8.0 mm
All your calculations in a single visual workspace
We combine chemistry logic, physical properties simulation, and B2B pricing parameters into a powerful node-based canvas.
Node-Based Editor
Connect ingredients, adjust active pharmaceutical ingredients (APIs), and preview formulation components dynamically.
Physical Simulator
Instant calculations of Carr's Index, Hausner Ratio, bulk and tapped densities to ensure blend flowability.
Chemical Compatibility
Real-time verification of raw material conflicts. Detect amino-sugar browning and lactose allergen conflicts.
GMP Documentation
Generate strict regulatory PDFs containing technological instructions, safety sheets, and digital validator signatures.
Why B2B Labs Choose PharmNode
How we compare to traditional scientific software classes
Canva for Chemists: Visual prototyping
AutoCAD is a powerful tool, but you wouldn't use it to design a simple social media post. Similarly, heavy molecular modeling packages are over-engineered for daily compounding. PharmNode provides a visual, drag-and-drop cloud alternative to prototype recipes in under 60 seconds.
Smart Canvas (Real-Time Checking)
Standard spreadsheets silently calculate formulas. PharmNode actively warns you of chemical conflicts (e.g. amine Maillard browning) before you touch a single gram of raw material.
10x Lower Entry Cost for QbD
Deploying enterprise compliance systems requires months and massive consultancy fees. PharmNode brings standard GxP validation tools to any team for $39/mo.
80% Lab Material Savings
Virtual screening lets you test 10 recipe variants online, discard 8 poor-flow or high-porosity versions, and test only the top 2 candidate mixtures in physical labs.
Traditional Solutions vs PharmNode
Comparison of traditional corporate software classes vs SaaS
| Software Class | Traditional Drawbacks & Cost | The PharmNode SaaS Solution |
|---|---|---|
| Heavy Molecular Software (CADD) | Costs $10k–$50k/yr. Requires a PhD in computational chemistry. Focuses on atomic behavior, which is useless for practical compounding of supplement blends. | Operates at the practical formulation level (excipients, binders, APIs). Requires zero training, runs in the browser, and is affordable for small teams. |
| Digital CMC / PLM Databases | Clunky, slow databases designed for regulatory filing. Boring spreadsheets tailored for compliance officers rather than R&D engineers. | Interactive, node-based Canvas. Technologists drag-and-drop ingredients and immediately see physical properties change visually in real-time. |
| Design of Experiments (DoE) Software | Requires you to run 15-20 physical experiments, waste kilograms of expensive raw materials, and manually input results to draw graphs. | Works BEFORE the physical lab. The expert rules identify issues like Maillard browning or compaction failure before you buy a single gram of raw material. |
From initial idea to tech spec in 3 simple steps
PharmNode streamlines drug design, replacing outdated Excel sheets with a digital decision support system.
- 1. Select Active IngredientAdd substances with pre-populated CAS numbers, densities, and safe limits.
- 2. Add Excipients & BindersTweak input percentages. The engine recalculates blend flowability and alerts you of errors.
- 3. Press Simulation & GMP ExportSet punch dimensions, calculate tablet porosity, and export validated technological logs.
PharmNode acts as a Decision Support System (DSS). All formulas are predictive. Physical laboratory validation (FTIR, DSC, HPLC) is strictly required before scale-up and industrial manufacturing.
Empowering Smart Pharmaceutical Design
PharmNode is a specialized Decision Support System (DSS) designed to bridge the gap between initial recipe formulation and regulatory-compliant manufacturing. Our mission is to replace time-consuming trial-and-error laboratory iterations with instant physical simulations and deterministic compatibility rules.
- 70%Reduction in R&D iteration cycles
- 0%Risk of cross-allergen or chemical conflicts
- 1 ClickTo generate GMP validation PDF reports
Who is PharmNode for?
- Technologists & FormulatorsAccelerate formulation design, calculate powder flowability (Carr & Hausner), and instantly resolve chemical conflicts.
- R&D LaboratoriesModel excipient and active ingredient interactions digitally before performing physical HPLC/DSC trials.
- Contract Manufacturers (CDMO)Optimize tablet press geometry, predict batch yields, and export ready-to-use GMP validation reports for clients.
Practical Examples of Formulation Engineering
Discover how technologists leverage PharmNode to resolve critical formulation, tableting, and compatibility challenges digitally.
- Solving poor flow in tablet compression
Excipient Flowability Tuning
ProblemA formulation with 15% Active Ingredient exhibits poor flowability (Carr Index of 25, Hausner Ratio of 1.33), causing weight variations during high-speed compression.SolutionAdding 1.5% Aerosil and 35% Avicel pH-102 adjusts tapped density, lowering the Carr Index to 12 (Excellent flow) and stabilizing tablet weight.VerificationFlow Index: Poor (25) → Excellent (12) - Preventing capping and lamination
Punch & Porosity Optimization
ProblemA 500mg Calcium Carbonate blend undergoes capping (top splits off) when pressed with a flat 10mm round punch under 15kN force.SolutionSwitching to a double-convex 11mm oval punch decreases tablet thickness, optimizes porosity to 15%, and guarantees safe mechanical strength at lower compression forces.VerificationForce Required: 15kN → 8kN - Detecting active/excipient conflicts
Allergen & Browning Prevention
ProblemDeveloping a new chewable tablet containing Glucosamine Hydrochloride (primary amine) and Lactose Monohydrate (reducing sugar).SolutionThe engine flags a Maillard browning conflict. Substituting lactose with Mannitol avoids discoloration, while removing lactose allergens under FALCPA/EFSA guidelines.VerificationCompatibility Rating: 40% → 100% Compliant
Built on State-of-the-Art Software Stack
We leverage industry-leading technologies to guarantee low latency, robust data storage, and compliance.
Next.js 16 & React 19
Fast hybrid server and client rendering with strict typing.
PostgreSQL & Prisma ORM
Safe relational storage of users, projects, and component schemas.
MongoDB Database
Flexible, high-performance storage for complex node-based canvas graphs.
Secure OAuth Security
Secure login utilizing NextAuth.js for corporate credentials.
Paddle Billing Engine
Instant subscription management for Pro plan.
Regulatory Compliance Standards
Our verification engine is engineered in collaboration with pharma consultants to comply with major legal environments.
FDA Title 21 CFR
Complies with digital signature requirements, dietary supplement labeling rules, and safe input thresholds.
EFSA Supplement Rules
Enforces metric parameters, EU allergens reporting, and EFSA maximum safe daily intake parameters.
Allergen Disclosures
Automatically profiles allergens and prints mandatory 'Contains' statements for allergens like lactose or gluten.
Choose your license
Test limits in real time. Switching plans instantly reconfigures canvas behavior.
Hobby
For independent technologists, students, and small startups.
- 3 ingredients max
- Base library (5 substances)
- Deterministic risk analysis
- AI substitution engine
- Export GMP PDF reports
Professional
For supplement manufacturers and contract developers.
- Unlimited ingredients in recipe
- Full raw material library (250+ excipients)
- AI auto-selection engine
- One-click chemical conflict resolution
- Export GMP PDF reports
Ready to optimize your formulations?
Start designing in our sandbox immediately. No credit card required.